CARD 11 Polyclonal Antibody, 50ul Organelle Studies Minichromosome maintenance complex component 3

Minichromosome maintenance complex component 3 encoded by MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication

Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation

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Mutations in this gene may result in Netherton syndrome

Phosphorylation stimulates binding to DNA and D-loop formation

CARD 11 Polyclonal Antibody, 50ul Organelle Studies Minichromosome maintenance complex component 3The protein encoded by CARD11 belongs to the membrane associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase associated recruitment domain (CARD). This protein has a domain structure similar to that of