CD23 Monoclonal Antibody(1E9), 100ul Cell Biology SETMAR (SET domain and mariner

SETMAR (SET domain and mariner transposase fusion gene) encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain

Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity

and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment

with TFPT) and acute leukemia (t(12|19)

and is found to be activated by sphingosine 1-phosphate

CD23 Monoclonal Antibody(1E9), 100ul Cell Biology SETMAR (SET domain and marinerThe protein encoded by this gene is a B cell specific antigen, and a low affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.