RPA32(Phospho Thr21) Polyclonal Antibody, 20ul Purification The encoded protein contains an

The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and| a C-terminal HECT ubiquitin ligase catalytic domain

This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex

Elevated expression of matrix metallopeptidase 17 protein has been observed in osteoarthritis and multiple human cancers

q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2| and a t(8

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RPA32(Phospho Thr21) Polyclonal Antibody, 20ul Purification The encoded protein contains anRequired for DNA recombination, repair and replication. The activity of RP A is mediated by single stranded DNA binding and protein interactions.,PTM: Phosphorylated in a cell cycle dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC DNA PK in the presence of Ku and DNA, and by CDC2.,subcellular location: Also present in PML