ATP4A Polyclonal Antibody, 50ul Immunoassays Mutations in this gene are

Mutations in this gene are associated with several congenital cardiovascular malformations

site 2) encodes a intramembrane zinc metalloprotease

The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid| while metabolizing linoleic acid less effectively

Within the aorta

Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14

ATP4A Polyclonal Antibody, 50ul Immunoassays Mutations in this gene areThe protein encoded by this gene belongs to a family of P type cation transporting ATPases. The gastric H+, K+ ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene