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DNA pol Epsilon A Polyclonal Antibody, 100ul Cell Function Analysis This protein may be important

SKU: 55715066422

4.2
PLN123.75 PLN168.75

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DNA pol Epsilon A Polyclonal Antibody, 100ul Cell Function Analysis This protein may be importantPOLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

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Description

This protein may be important in hormonal control of glycogen metabolism

Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor

and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells

Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA

DNA pol Epsilon A Polyclonal Antibody, 100ul Cell Function Analysis This protein may be importantPOLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

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