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ERF Polyclonal Antibody, 50ul[BT-AP03050] Hepatocytes Knockout studies in mice suggest

SKU: 55572510819

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ERF Polyclonal Antibody, 50ul[BT-AP03050] Hepatocytes Knockout studies in mice suggestETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by ERF binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene.

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Description

Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system

stabilizes p53/TP53 by affecting its interaction with ubiquitin ligase MDM2 (PubMed: 25732823)

but no cytoplasmic death domain

All family members are proline and glutamine-rich

This gene encodes a member of the collapsin response mediator protein family

ERF Polyclonal Antibody, 50ul[BT-AP03050] Hepatocytes Knockout studies in mice suggestETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by ERF binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene.

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