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POLH Polyclonal Antibody, 100ul Custom RNA Oligos Androgen-induced 1 (AIG1) is a

SKU: 5547850240

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POLH Polyclonal Antibody, 100ul Custom RNA Oligos Androgen-induced 1 (AIG1) is aThis gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA directed polymerases. However, it accurately replicates UV damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV induced DNA damage. This polymerase is thought to be

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Description

Androgen-induced 1 (AIG1) is a novel Pirh2-interacting protein

The expression of this gene appears to be restricted to spermatocytes

Alternative splicing results in multiple transcripts variants

are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals

and barely detectable level in the peripheral leukocytes

POLH Polyclonal Antibody, 100ul Custom RNA Oligos Androgen-induced 1 (AIG1) is aThis gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA directed polymerases. However, it accurately replicates UV damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV induced DNA damage. This polymerase is thought to be

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