FKTN Polyclonal Antibody, 100ul Pipette Filler The ARF4 gene spans approximately

The ARF4 gene spans approximately 12kb and contains six exons and five introns

Alternatively spliced transcript variants encoding multiple isoforms have been observed for ABCB7

A mutation in this gene was associated with microphthalmia| syndromic 13

Seems to be coupled to the G(i)/G(o)

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

FKTN Polyclonal Antibody, 100ul Pipette Filler The ARF4 gene spans approximatelyThe protein encoded by this gene is a putative transmembrane protein that is localized to the cis Golgi compartment, where it may be involved in the glycosylation of alpha dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama type congenital muscular dystrophy (FCMD), Walker Warburg syndrome (WWS), limb girdle muscular