ET-1 Polyclonal Antibody, 50ul Vacuum Filter 2001 [PubMed 12063393])
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ET-1 Polyclonal Antibody, 50ul Vacuum Filter 2001 [PubMed 12063393])EDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
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