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Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Additionally| this gene supports metastatic

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Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Additionally| this gene supports metastaticThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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Description

Additionally| this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer

and has glycosaminoglycan attachment sites in the acidic C-terminal region

and is a diagnostic marker for some human diseases

This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis

Two alternatively spliced transcript variants encoding the same protein have been reported

Axl Polyclonal Antibody, 100ul[BT-AP00783] Dry Bath Additionally| this gene supports metastaticThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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