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Histone H2A Polyclonal Antibody, 100ul[BT-AP03998] Pipette Micro Tips BAGE2 is a candidate gene

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Histone H2A Polyclonal Antibody, 100ul[BT-AP03998] Pipette Micro Tips BAGE2 is a candidate geneHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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Description

BAGE2 is a candidate gene encoding tumor antigens

Component of the transcription regulatory histone acetylation (HAT) complex SAGA

which is proteolytically processed to its active form by caspase 1 (CASP1/ICE)

It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit

and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions

Histone H2A Polyclonal Antibody, 100ul[BT-AP03998] Pipette Micro Tips BAGE2 is a candidate geneHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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