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MBD2 Rabbit Polyclonal Antibody, 100ul Cellular Function Assays so that the gene pair

SKU: 55078876883

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MBD2 Rabbit Polyclonal Antibody, 100ul Cellular Function Assays so that the gene pairDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2 MBD1 MBD2 MBD3 and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl CpG binding domain (MBD). Each of these proteins with the exception of MBD3 is capable of binding specifically to methylated DNA. MECP2 MBD1 and MBD2 can also repress transcription from methylated gene

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Description

so that the gene pair shares a common promoter

In vitro assays indicate the protein lacks phosphorylation activity

General transcription factor 3C polypeptide 3 encoded by GTF3C3 is part of the TFIIIC2 complex

Alternative splicing may result in several transcript variants| however

This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52

MBD2 Rabbit Polyclonal Antibody, 100ul Cellular Function Assays so that the gene pairDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2 MBD1 MBD2 MBD3 and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl CpG binding domain (MBD). Each of these proteins with the exception of MBD3 is capable of binding specifically to methylated DNA. MECP2 MBD1 and MBD2 can also repress transcription from methylated gene

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