KREM1 Polyclonal Antibody, 50ul Serum Multiple heterogeneous transcriptional start sites

Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported

Multiple pseudogenes of this gene have been identified in the genome

Many alternatively spliced transcript variants encoding different isoforms have been described

A number of alternatively spliced variants encoding distinct isoforms have been described

A pseudogene of this gene is located on the long arm of chromosome 3

KREM1 Polyclonal Antibody, 50ul Serum Multiple heterogeneous transcriptional start sitesThis gene encodes a high affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT) beta catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have