p53(Phospho Ser392) Polyclonal Antibody, 100ul Plasmid Preparation Acyl-coenzyme A thioesterase 4 is

Acyl-coenzyme A thioesterase 4 is an enzyme encoded by the ACOT4 gene in humans and is mapped to chromosome 14

This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions

A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13

May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation

It functions as an oxidoreductase| and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways| promote mitochondrial biogenesis and mitochondrial function| and suppress cellular senescence through genome maintenance and redox regulation

p53(Phospho Ser392) Polyclonal Antibody, 100ul Plasmid Preparation Acyl-coenzyme A thioesterase 4 isThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.