Human Trichoplein Keratin Filament-binding Protein, TCHP ELISA Kit , 96T Modified Oligos and promoting cytoskeletal reorganization
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Human Trichoplein Keratin Filament-binding Protein, TCHP ELISA Kit , 96T Modified Oligos and promoting cytoskeletal reorganizationTumor suppressor which has the ability to inhibit cell growth and be pro apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8 K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:
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