FTO Polyclonal Antibody, 100ul Cell Culture Plates the descending thoracic aorta

the descending thoracic aorta

May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa

Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid

Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon

This protein forms a trimeric complex with cyclin H and MAT2

FTO Polyclonal Antibody, 100ul Cell Culture Plates the descending thoracic aortaFTO is a nuclear protein of the AlkB related non haem iron and 2 oxoglutarate dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.