IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04676] Cell Function Analysis An alternative splice variant has

An alternative splice variant has been described but its full length sequence has not been determined

Endoplasmic reticulum aminopeptidase 1 encoded by ERAP1 is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules

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Both actins and ARPs have an actin fold

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IKappaB- Alpha Polyclonal Antibody, 20ul[BT-AP04676] Cell Function Analysis An alternative splice variant hasNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell