PRAK Monoclonal Antibody, 50ul DNA Fragments Mutations in this gene cause

Mutations in this gene cause porencephaly

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multiple endocrine neoplasia

the encoded protein binds to the putative leucine zipper domain of macroH2A1

Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs

PRAK Monoclonal Antibody, 50ul DNA Fragments Mutations in this gene causeThe protein encoded by this gene is a tumor suppressor and member of the serine threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1 ERK, MAPK14 p38 alpha, and MAPK11 p38 beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein