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TM165 Rabbit Polyclonal Antibody, 20ul Recombinant Protein The protein encoded by IL36RN

SKU: 54212603588

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TM165 Rabbit Polyclonal Antibody, 20ul Recombinant Protein The protein encoded by IL36RNThis gene encodes a predicted transmembrane protein with a perinuclear Golgi like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

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Description

The protein encoded by IL36RN (interleukin 36 receptor antagonist) is a member of the interleukin 1 cytokine family

or changes in metabolism

PPARs affect the expression of target genes involved in cell proliferation

suggesting that it functions as a transcription factor

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TM165 Rabbit Polyclonal Antibody, 20ul Recombinant Protein The protein encoded by IL36RNThis gene encodes a predicted transmembrane protein with a perinuclear Golgi like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants.

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