NFκB-p105(Phospho Ser927) Polyclonal Antibody, 50ul Lentiviral Packaging Human IF-2(mt) shares 32 to

Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s| with the greatest degree of conservation in the G domains of the proteins

Involved in vesicular transport between the endoplasmic reticulum and the Golgi

A mutations in this gene is associated with autosomal dominant macrothrombocytopenia

The delta locus is situated within the alpha locus| between the alpha V and J segments

Belongs to the Sp1 C2H2-type zinc-finger protein family

NFκB-p105(Phospho Ser927) Polyclonal Antibody, 50ul Lentiviral Packaging Human IF-2(mt) shares 32 toThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and