RANB3 Rabbit Polyclonal Antibody, 50ul Shakers Breast cancer metastasis-suppressor 1 encoded

Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC)

All variants share the N-terminal region in common

This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells

This gene is clustered with family members FADS1 and FADS2 at 11q12-q13

It encodes Disintegrin and metalloproteinase domain-containing protein 10 with similarity to collagens X and VIII and complement factor C1q

RANB3 Rabbit Polyclonal Antibody, 50ul Shakers Breast cancer metastasis-suppressor 1 encodedThis gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice variants encoding different isoforms have been characterized.