HGK Monoclonal Antibody, 100ul[BT-MCA0674] Protein Analysis A pseudogene of this gene

A pseudogene of this gene is located on the short arm of chromosome 9

High levels also detected in liver

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This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA)

This gene has been localized to a cluster of related genes at chromosome region 5q31

HGK Monoclonal Antibody, 100ul[BT-MCA0674] Protein Analysis A pseudogene of this geneThe protein encoded by this gene is a member of the serine threonine protein kinase family. This kinase has been shown to specifically activate MAPK8 JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant negative mutants of MAP3K7 TAK1, MAP2K4 MKK4, and MAP2K7 MKK7, which suggests that this kinase may function through the MAP3K7 MAP2K4 MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. Alternatively