PDE1A Polyclonal Antibody, 20ul Inoculating Loops/Needles a PDZ domain at the

a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal

treatment with either agent alone only achieves reversible differentiation

and interact with various ligands to influence cell growth

This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells

It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif

PDE1A Polyclonal Antibody, 20ul Inoculating Loops/Needles a PDZ domain at theCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and or cGMP to their respective nucleoside 5 prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+) calmodulin (see CALM1; MIM 114180) dependent PDEs (CaM PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001