TBL1XR1 Monoclonal Antibody, 100ul Cell Culture & Maintenance This gene is localized in

This gene is localized in the DSS (dosage-sensitive sex reversal) critical region

and ADCAIII often referred to as the 'pure' cerebellar syndrome (SCA5)

Contains 3 REM (Hr1) repeats

The deduced amino acid sequence exhibits 33% similarity with CD38

Activity of this proten is important in the immune system

TBL1XR1 Monoclonal Antibody, 100ul Cell Culture & Maintenance This gene is localized inThis gene is a member of the WD40 repeat containing gene family and shares sequence similarity with transducin (beta) like 1X linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum