SG11A Rabbit Polyclonal Antibody, 20ul Enzyme Activity Assays Mutation of this gene causes

Mutation of this gene causes North American Indian childhood cirrhosis

Four alternatively spliced transcript variants of MAPK14 encoding distinct isoforms have been reported

and thus activated by JNK kinases

It is the major substrate of protein kinases in the ribosome

These variants encode different isoforms| which are differentially expressed and have different kinase activities

SG11A Rabbit Polyclonal Antibody, 20ul Enzyme Activity Assays Mutation of this gene causesThis gene encodes several androgen dependent epididymis specific secretory proteins. The specific functions of these proteins have not been determined but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta defensins a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants