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Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification The mitogen-activated protein kinase 8

SKU: 52657352443

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Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification The mitogen-activated protein kinase 8NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

The mitogen-activated protein kinase 8 interacting protein 2 encoded by MAPK8IP2 is closely related to MAPK8IP1/IB1/JIP-1

100% undergone for production line air tightness test

GO annotations related to this gene include poly (A) RNA binding and protein kinase activity

This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5

One isoform lacks the intermembrane region and is secreted outside the cell

Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification The mitogen-activated protein kinase 8NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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