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IGF-IR Polyclonal Antibody, 50ul[BT-AP04397] Cell Separation and Collection induces dimerization and activation of

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IGF-IR Polyclonal Antibody, 50ul[BT-AP04397] Cell Separation and Collection induces dimerization and activation ofIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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Description

induces dimerization and activation of the receptor

The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs

In response to cellular stress and proinflammatory cytokines

Alternatively spliced transcript variants encoding multiple isoforms have been observed for URI1

which play a role in a wide range of developmental processes

IGF-IR Polyclonal Antibody, 50ul[BT-AP04397] Cell Separation and Collection induces dimerization and activation ofIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms

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