Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Within leukocyte population more abundant

Within leukocyte population more abundant expression in neutrophils and eosinophils

This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase

|tissue specificity:Expressed in skeletal muscle

Higher expression levels of RPS19 in some primary colon carcinomas compared to matched normal colon tissues has been observed

This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity

Raf-1(Phospho Tyr341) Polyclonal Antibody, 50ul Custom DNA Oligos Within leukocyte population more abundantThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.