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TRADD Polyclonal Antibody, 100ul Hepatocytes The functioning of this gene

SKU: 51865775390

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TRADD Polyclonal Antibody, 100ul Hepatocytes The functioning of this geneTumor necrosis factor receptor type 1 associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A TNFR1 and mediates programmed cell death signaling and NF kappaB activation. Tumor necrosis factor receptor type 1 associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor of apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated

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Description

The functioning of this gene is implicated in a wide variety of inflammation-associated disease states

Alternatively spliced transcript variants encoding multiple isoforms have been observed for ITCH

It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation

and whose properties are determined by subunit composition

It has been associated with multiple functions| including axon membrane trafficking| axonal homeostasis| mitophagy| adipose differentiation| and hematopoietic stem cell maintenance

TRADD Polyclonal Antibody, 100ul Hepatocytes The functioning of this geneTumor necrosis factor receptor type 1 associated DEATH domain protein encoded by TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A TNFR1 and mediates programmed cell death signaling and NF kappaB activation. Tumor necrosis factor receptor type 1 associated DEATH domain protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor of apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated

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