Raf-1(Phospho Thr269) Polyclonal Antibody, 100ul Mammalian Expression phospholipase A

phospholipase A

Two pseudogenes of this gene have been identified on chromosomes 10 and 4

Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders

is an actin-related protein

CLIP2 is hemizygously deleted in Williams syndrome

Raf-1(Phospho Thr269) Polyclonal Antibody, 100ul Mammalian Expression phospholipase AThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.