PGS1 Polyclonal Antibody, 100ul Cryopreservation Transcript variants utilizing alternative polyA

Transcript variants utilizing alternative polyA sites exist

Mutations in this gene cause ulnar-mammary syndrome

Alternate splicing results in multiple transcript variants

The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins

and regulates centriole duplication during the cell cycle

PGS1 Polyclonal Antibody, 100ul Cryopreservation Transcript variants utilizing alternative polyAThis gene encodes a member of the small leucine rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve