p53 Polyclonal Antibody, 20ul[BT-AP06833] Pathway and Network Analysis PTCH1 (patched 1) encodes a

PTCH1 (patched 1) encodes a member of the patched gene family

Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease

FAT10 is inducible by interferon-g and tumor necrosis factor a (TNF)

Sulfatases (EC 3

CD30 ligand (CD30L)/TNFSF8 is a type II membrane protein belonging to the TNF superfamily

p53 Polyclonal Antibody, 20ul[BT-AP06833] Pathway and Network Analysis PTCH1 (patched 1) encodes aTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.