JMJD2B Polyclonal Antibody, 20ul Miscellaneous Increases firing activity and intracellular

Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons

There is a pseudogene for ALMS1 located adjacent in the same region of chromosome 2

This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation

while the sterilization process eliminates contamination risks

while loss of heterozygosity of DMTN is thought to play a role in prostate cancer progression

JMJD2B Polyclonal Antibody, 20ul Miscellaneous Increases firing activity and intracellularHistone demethylase that specifically demethylates 'Lys 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys 4', H3 'Lys 27', H3 'Lys 36' nor H4 'Lys 20'. Only able to demethylate trimethylated H3 'Lys 9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.