FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This protein preferentially induces apoptosis
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FEN-1 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation This protein preferentially induces apoptosisFlap endonuclease 1 encoded by FEN1 removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG RAD2 endonuclease family and is
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