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FURIN Polyclonal Antibody, 50ul Cell Labeling & Imaging mutations in CHEK2 are thought

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FURIN Polyclonal Antibody, 50ul Cell Labeling & Imaging mutations in CHEK2 are thoughtThis gene encodes a member of the subtilisin like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts

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Description

mutations in CHEK2 are thought to confer a predisposition to sarcomas

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes

Contains 1 SURP motif repeat

Component of the little elongation complex (LEC)

FURIN Polyclonal Antibody, 50ul Cell Labeling & Imaging mutations in CHEK2 are thoughtThis gene encodes a member of the subtilisin like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts

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