TRPM4 Rabbit Polyclonal Antibody, 100ul Filtration This gene encodes a secreted

This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes

like most family members

The encoded protein (sphingosine-1-phosphate receptor 2) is a receptor for sphingosine 1-phosphate

The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors

This protein is overexpressed in epithelial mesotheliomas| ovarian cancers and in specific squamous cell carcinomas

TRPM4 Rabbit Polyclonal Antibody, 100ul Filtration This gene encodes a secretedThe protein encoded by this gene is a calcium activated nonselective ion channel that mediates transport of monovalent cations across membranes thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration but this channel does not transport calcium.