InsP 3-kinase B Polyclonal Antibody, 50ul Cell Separation and Collection RNA polymerase II transcription regulatory

RNA polymerase II transcription regulatory region sequence-specific binding

At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene

The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related))

and which specifically associates with spliced mRNA and not with unspliced pre-mRNA

5'-tetraiodothyronine

InsP 3-kinase B Polyclonal Antibody, 50ul Cell Separation and Collection RNA polymerase II transcription regulatoryThe protein ITPKB encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5 trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium calmodulin and protein phosphorylation mechanisms control its activity.