ST2A1 Polyclonal Antibody, 50ul[BT-AP14510] Enzyme Activity Assays This gene is a tumor

This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding

Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats| and an intracellular domain consisting of multiple different domain types

together with SNAP25 (synaptosome-associated protein of 25 kDa)

The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain

The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system

ST2A1 Polyclonal Antibody, 50ul[BT-AP14510] Enzyme Activity Assays This gene is a tumorThis gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome.