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IRF-3 Polyclonal Antibody, 20ul[BT-AP04628] Human Genome Knockout Libraries This protein is reported to

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IRF-3 Polyclonal Antibody, 20ul[BT-AP04628] Human Genome Knockout Libraries This protein is reported toIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed

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Description

This protein is reported to interact with other CARD domain containing proteins including CARD9

C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit

ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium

and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions

most of which are necessary for proper CEP55 function

IRF-3 Polyclonal Antibody, 20ul[BT-AP04628] Human Genome Knockout Libraries This protein is reported toIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed

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