SPE39 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance with symptoms including severe mononucleosis

with symptoms including severe mononucleosis and malignant lymphoma

The promoter of this gene is frequently hypermethylated in these cancer tissues| although the hypermethylation does not appear to be the cause of the reduced expression of this gene

This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses

The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates

DYRK1A is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene

SPE39 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance with symptoms including severe mononucleosisThis gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis renal dysfunction and cholestasis 2). Alternative splicing results in multiple transcript variants.