BBS7 Rabbit Polyclonal Antibody, 50ul Palm Micro Centrifuges This protein is one of

This protein is one of the main cytolytic proteins of cytolytic granules

Defects in TRPS1 are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III

The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme

It regulates circulating fetal thyroid hormone concentrations

which includes three known members located adjacent to each other on the long arm of chromosome 7

BBS7 Rabbit Polyclonal Antibody, 50ul Palm Micro Centrifuges This protein is one ofThis gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin like BBS proteins (BBS6, BBS10, and BBS12) and CCT TRiC family chaperonins. Mutations in this gene are implicated in Bardet Biedl syndrome,