EFS Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation Marfan syndrome is associated with

Marfan syndrome is associated with chromosome 15 through the FBN1 gene

An important paralog of this gene is USP4

Two transcript variants encoding the same protein have been found for APOL2

It is similar to a rat protein which is a specific partner for the tail domain of myosin V

Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia

EFS Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation Marfan syndrome is associated withThe longest protein isoform encoded by this gene contains an SH3 domain which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene.