PHF1 Polyclonal Antibody, 20ul Vector Construction MIM 600892) (bHLH-PAS) class of

MIM 600892) (bHLH-PAS) class of transcriptional regulators

but activates transcription when Ras is present

The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors

The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue

CBFA2T3 is also a putative breast tumor suppressor

PHF1 Polyclonal Antibody, 20ul Vector Construction MIM 600892) (bHLH-PAS) class ofPHF1 encodes a Polycomb group protein. PHD finger protein 1 is a component of a histone H3 lysine 27 (H3K27) specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. PHD finger protein 1 is also recruited to double strand breaks, and reduced protein levels results in X ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for PHF1.