SDHF1 Rabbit Polyclonal Antibody, 20ul In vitro Assessment This gene encodes a nuclear

This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus

Alternatively spliced transcript variants encoding multiple isoforms have been observed for SPHK2

An important paralog of this gene is ZMYM6

Mutations in this gene cause platelet glycoprotein deficiency

This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides

SDHF1 Rabbit Polyclonal Antibody, 20ul In vitro Assessment This gene encodes a nuclearThe succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain is composed of 4 individual subunits. The protein encoded by this gene resides in the mitochondria and is essential for SDH assembly but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH defective infantile leukoencephalopathy (mitochondrial complex II deficiency).