FILA2 Rabbit Polyclonal Antibody, 20ul Filtration in addition to binding Ca2+

in addition to binding Ca2+

where it is induced by ER stress caused by malfolded proteins

and angiotensin II into the vasodilator angiotensin 1-7

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When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner

FILA2 Rabbit Polyclonal Antibody, 20ul Filtration in addition to binding Ca2+The filaggrin like protein encoded by this gene is upregulated by calcium proteolyzed by calpain 1 and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact in addition to providing a physical barrier C terminal fragments of this protein display antimicrobial activity