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LYOX Rabbit Polyclonal Antibody, 50ul Sealing Film |pharmaceutical:A constitutively active FOXO4 mutant

SKU: 4747581273

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LYOX Rabbit Polyclonal Antibody, 50ul Sealing Film |pharmaceutical:A constitutively active FOXO4 mutant

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Description

|pharmaceutical:A constitutively active FOXO4 mutant where phosphorylation sites Thr-32| Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival| transformation and tumorigenicity

the C-terminal kinase domain binds to its own N-terminal region

tongue and small intestine and in endocrine glands such as thyroid and adrenal gland

a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al

The product of this gene is one of three related chemokines that specifically activate chemokine receptor CCR3

LYOX Rabbit Polyclonal Antibody, 50ul Sealing Film |pharmaceutical:A constitutively active FOXO4 mutant

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