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PERK Polyclonal Antibody, 20ul[BT-AP07066] Cellular Function Assays which bind microtubules

SKU: 46825718108

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PERK Polyclonal Antibody, 20ul[BT-AP07066] Cellular Function Assays which bind microtubulesEukaryotic translation initiation factor 2 alpha kinase 3 encoded by EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 3 is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic

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Description

which bind microtubules

Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis

Alternative splicing occurs at DGKZ and multiple transcript variants encoding distinct isoforms have been identified

Two transcript variants resulting from alternative splicing have been identified

REL (REL proto-oncogene

PERK Polyclonal Antibody, 20ul[BT-AP07066] Cellular Function Assays which bind microtubulesEukaryotic translation initiation factor 2 alpha kinase 3 encoded by EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 3 is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic

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