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Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing Mutation of this gene results

SKU: 46439814374

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Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing Mutation of this gene resultsThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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Description

Mutation of this gene results in neuropathy and optic atrophy

Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity)

Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease

TORC1 binds to and is inhibited by FKBP12-rapamycin

This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins

Flt3 Polyclonal Antibody, 100ul[BT-AP09206] Gene Editing Mutation of this gene resultsThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis,

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