p53 Polyclonal Antibody, 50ul[BT-AP06829] Centrifugal Filter Pseudogenes of NFE2L3 are found

Pseudogenes of NFE2L3 are found on chromosomes 16

The protein thus belongs to the suppressor of cytokine signaling (SOCS)

or xeroderma pigmentosum VI (XP6)

The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains

and may play a role in protection from oxidative stress

p53 Polyclonal Antibody, 50ul[BT-AP06829] Centrifugal Filter Pseudogenes of NFE2L3 are foundTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.