PC-PLD1 Polyclonal Antibody, 100ul[BT-AP06983] ADME Mutations in the GPIb beta

Mutations in the GPIb beta subunit have been associated with Bernard-Soulier syndrome

The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution

This gene encodes lipopolysaccharide-induced TNF-alpha factor

liver and brain but not in other tissues

mammary gland

PC-PLD1 Polyclonal Antibody, 100ul[BT-AP06983] ADME Mutations in the GPIb betaPLD1 (phospholipase D1) encodes a phosphatidylcholine specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties.